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不同倍性肝细胞肝细胞核染色质的年龄相关变化。

Age-related changes in chromatin of liver cell nuclei of different ploidity.

作者信息

Myśliwski A, Myśliwska J, Kmieć Z

出版信息

Histochemistry. 1977 Apr 20;52(1):91-6. doi: 10.1007/BF00495818.

Abstract

A comparison of the Feulgen hydrolysis curves and the chromatin compactness of the liver cell nuclei of young and old rats was made. It was found that the rate of DNA depurination and chromatin compactness are higher in the liver cell nuclei of old rats, both in di-and tetraploidal cells. The effect of fixation upon the course of the hydrolysis curves is discussed.

摘要

对年轻和老年大鼠肝细胞细胞核的福尔根水解曲线和染色质紧密程度进行了比较。结果发现,无论是二倍体细胞还是四倍体细胞,老年大鼠肝细胞细胞核中的DNA脱嘌呤速率和染色质紧密程度都更高。讨论了固定对水解曲线进程的影响。

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