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二氧化碳对青蛙肌肉细胞内钾的一些影响。

Some effects of carbon dioxide on intracellular potassium in frog muscle.

作者信息

Huguenin F

出版信息

Respir Physiol. 1982 Feb;47(2):141-50. doi: 10.1016/0034-5687(82)90107-4.

DOI:10.1016/0034-5687(82)90107-4
PMID:6803315
Abstract

The short-term effect of carbon dioxide on resting potential (Em), intracellular potassium activity (aiK) and intracellular pH (pHi) has been investigated in frog skeletal muscle. The external pH was kept constant in the range 6.8-7.6 by addition of HCO-3 in presence of CO2. Measurements were done in single or surface fibres of the semitendinosus muscle. CO2 reduced quickly Em and aiK at high but not at low PCO2. This effect persisted in presence of ouabain (10(-5) M). These actions of CO2 are largely accountable for by osmotic swelling, but additional factors are involved.

摘要

在青蛙骨骼肌中研究了二氧化碳对静息电位(Em)、细胞内钾活性(aiK)和细胞内pH值(pHi)的短期影响。通过在二氧化碳存在下添加HCO-3,将外部pH值保持在6.8 - 7.6的恒定范围内。测量是在半腱肌的单根或表面纤维中进行的。在高PCO2时,二氧化碳能迅速降低Em和aiK,但在低PCO2时则不然。在哇巴因(10^(-5) M)存在的情况下,这种效应仍然存在。二氧化碳的这些作用在很大程度上是由渗透性肿胀引起的,但还涉及其他因素。

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