Friedrich F, Kemeter P
Wien Med Wochenschr. 1982 Jan 15;132(1):19-21.
29 amenorrhoic women were treated with the Buserelin nasal spray (HOE 766) developed by Hoechst A. G. in a dosis of 50 microgram daily during 2 weeks. 22 of the patients desired restoration of menstrual cycle, 7 women were wanting a child. As result of the treatment 16 women menstruated, 6 ovulated, 2 became pregnant. With Buserelin nasal spray menstruation was induced in 12 out of 16 women with amenorrhea WHO group II.
29名闭经女性使用赫斯特股份公司研发的布舍瑞林鼻喷雾剂(HOE 766)进行治疗,剂量为每日50微克,持续2周。22名患者希望恢复月经周期,7名女性想要孩子。治疗结果显示,16名女性月经来潮,6名排卵,2名怀孕。在WHO II组的16名闭经女性中,使用布舍瑞林鼻喷雾剂诱导12名女性月经来潮。