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左乳癌患者术后放疗后心脏损害的心电图研究(作者译)

[An electrocardiographic study of cardiac damage following post-operative radiation in patients with mammary carcinoma on the left (author's transl)].

作者信息

Wehr M, Rosskopf B G, Schwenk D, Prignitz R

出版信息

Z Kardiol. 1982 Jan;71(2):112-8.

PMID:6803466
Abstract

Systematic ECG-analysis were performed in 13 patients (mean age 55.1 years) with mammary carcinoma on the left, prior to, during, and 4 months after postoperative radiation therapy. Treatment was done with a gammatron, the average load to the anterior cardiac wall amounted to 36 Gy. All patients exhibited ST-T segment changes, flat, isoelectric or coronary negative T-waves in the precordial leads demonstrating radiation-induced perimyocarditis. Prolongation of QT-interval corrected with Bazett's formula (QTc) was observed in 6 patients showing myocardial damage. Sinus tachycardia in 9 patients and lower voltage in 3 patients gave a hint to early appearance of pericardial effusions. Pulmonary P-waves in 6 patients and shift of QRS-axis to the right in 5 patients demonstrated early damage of the right heart. Clinical deterioration could not be seen in any patient.

摘要

对13例左侧乳腺癌患者(平均年龄55.1岁)在术后放疗前、放疗期间及放疗后4个月进行了系统的心电图分析。采用伽马治疗机进行治疗,心脏前壁的平均照射剂量为36 Gy。所有患者均出现ST-T段改变,胸前导联出现平坦、等电位或冠状T波倒置,提示放射性心包心肌炎。6例患者观察到用巴泽特公式校正的QT间期(QTc)延长,提示心肌损伤。9例患者出现窦性心动过速,3例患者出现低电压,提示早期心包积液。6例患者出现肺型P波,5例患者QRS电轴右偏,提示右心早期损伤。所有患者均未出现临床病情恶化。

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