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[左侧乳腺癌女性患者术后高压治疗期间的心脏功能]

[Heart function during postoperative high-voltage therapy in female patients with left-sided breast cancer].

作者信息

Wehr M, Rosskopf B G, Pittner P M, Schwenk D, Prignitz R

出版信息

Klin Wochenschr. 1982 Dec 15;60(24):1505-7. doi: 10.1007/BF01716103.

DOI:10.1007/BF01716103
PMID:7166929
Abstract

Systolic time intervals according the method of Weissler were measured in nine females (mean age: 55.1 years) with mammary carcinoma on the left, prior to, during and 3 months after postoperative radiation therapy. The average load to the anterior cardiac wall amounted to 36 Gy. We found a reversible statistically highly significant decrease of left ventricular function (increase of PEP/LVET) during radiation therapy, which seems to be related to a radiation-induced acute pancarditis known from animal experiments.

摘要

根据魏斯勒方法,对9名左侧患乳腺癌的女性(平均年龄:55.1岁)在术后放疗前、放疗期间及放疗后3个月测量了收缩期时间间期。心脏前壁的平均照射剂量为36戈瑞。我们发现放疗期间左心室功能出现可逆性的、具有统计学高度显著性的下降(PEP/LVET增加),这似乎与动物实验中已知的放射性急性全心炎有关。

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[Heart function during postoperative high-voltage therapy in female patients with left-sided breast cancer].[左侧乳腺癌女性患者术后高压治疗期间的心脏功能]
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2
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Subclinical cardiotoxicity detected by strain rate imaging up to 14 months after breast radiation therapy.在乳腺癌放疗后 14 个月,通过应变率成像检测到亚临床心脏毒性。
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Radiat Oncol. 2015 Jul 10;10:141. doi: 10.1186/s13014-015-0436-2.
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Adjuvant hypofractionated versus conventional whole breast radiation therapy for early-stage breast cancer: long-term hospital-related morbidity from cardiac causes.早期乳腺癌辅助性低分割与常规全乳放射治疗比较:心脏相关原因导致的长期住院相关发病率。
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[ECG-changes following postoperative irradiation of patients with mammary carcinoma (author's transl)].乳腺癌患者术后放疗后的心电图变化(作者译)
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引用本文的文献

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The choice of multi-beam IMRT for whole breast radiotherapy in early-stage right breast cancer.早期右乳腺癌全乳放疗中多束调强放疗的选择。
Springerplus. 2016 May 28;5(1):688. doi: 10.1186/s40064-016-2314-2. eCollection 2016.
2
Treatment techniques to reduce cardiac irradiation for breast cancer patients treated with breast-conserving surgery and radiation therapy: a review.治疗技术可减少保乳手术和放射治疗的乳腺癌患者的心脏照射:综述。
Front Oncol. 2014 Nov 14;4:327. doi: 10.3389/fonc.2014.00327. eCollection 2014.

本文引用的文献

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2
[An electrocardiographic study of cardiac damage following post-operative radiation in patients with mammary carcinoma on the left (author's transl)].左乳癌患者术后放疗后心脏损害的心电图研究(作者译)
Z Kardiol. 1982 Jan;71(2):112-8.
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Radiation heart disease. Analysis of 16 young (aged 15 to 33 years) necropsy patients who received over 3,500 rads to the heart.
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Dose and treatment factors in radiation-related pericardial effusion associated with the mantle technique for Hodgkin's disease.
Cancer. 1975 Mar;35(3):795-802. doi: 10.1002/1097-0142(197503)35:3<795::aid-cncr2820350335>3.0.co;2-m.