Ben-Zvi Z, Spohn W A, Young S H, Kattan M
Am Rev Respir Dis. 1982 Apr;125(4):392-5. doi: 10.1164/arrd.1982.125.4.392.
Hypnosis has been used for many years in the treatment of asthma, but studies of its usefulness have been controversial. We assessed the efficacy of hypnosis in attenuating exercise-induced asthma (EIA) in 10 stable asthmatics. The subjects ran on a treadmill while mouth breathing for 6 min on 5 different days. Pulmonary mechanics were measured before and after each challenge. Two control exercise challenges resulted in a reproducible decrease in forced expiratory volume in one second (FEV1). On 2 other days, saline or cromolyn by nebulization was given in a double-blind manner with the suggestion that these agents would prevent EIA. Hypnosis prior to exercise resulted in a 15.9% decrease in FEV1 compared with a 31.8% decrease on the control days (p less than 0.001). Pretreatment with cromolyn resulted in a 7.6% decrease in FEV1. We conclude that hypnosis can alter the magnitude of a pathophysiologic process, namely, the bronchospasm after exercise in patients with asthma.
多年来，催眠疗法一直被用于治疗哮喘，但关于其有效性的研究一直存在争议。我们评估了催眠疗法对10名稳定期哮喘患者运动诱发性哮喘（EIA）的缓解效果。受试者在跑步机上进行口呼吸跑步，共5天，每天6分钟。在每次运动激发前后测量肺力学指标。两次对照运动激发导致一秒用力呼气量（FEV1）出现可重复的下降。在另外两天，以双盲方式给予雾化生理盐水或色甘酸钠，并暗示这些药物可预防EIA。运动前进行催眠，FEV1下降了15.9%，而对照日下降了31.8%（p<0.001）。色甘酸钠预处理使FEV1下降了7.6%。我们得出结论，催眠可以改变病理生理过程的程度，即哮喘患者运动后的支气管痉挛。
