Preece P E, Baum M, Mansel R E, Webster D J, Fortt R W, Gravelle I H, Hughes L E
Br Med J (Clin Res Ed). 1982 May 1;284(6325):1299-300. doi: 10.1136/bmj.284.6325.1299.
The importance of pain as a presenting symptom of breast cancer has been assessed in a series of 240 patients with operable breast cancer over four years. From an analysis of the case histories of 36 patients the diagnosis proved difficult in one-quarter of the cancers. This is explained by the high incidence of subclinical and lobular carcinoma in the group. Cancer must be seriously considered as a diagnosis in patients presenting with well-localised breast pain of recent onset. These patients should be followed for at least one year after the onset of the pain before cancer is confidently excluded.
在四年期间,对240例可手术乳腺癌患者进行了一系列研究,以评估疼痛作为乳腺癌首发症状的重要性。通过对36例患者病历的分析发现,四分之一的癌症诊断存在困难。这是由于该组中亚临床癌和小叶癌的高发病率所致。对于近期出现乳房局限性疼痛的患者,必须认真考虑癌症的诊断。在确诊排除癌症之前,这些患者在疼痛出现后应至少随访一年。