Mouriquand J, Mouriquand C, Sage J C, Saez S, Jacrot M, Gabelle P
C R Seances Acad Sci III. 1981 Dec 21;293(15):801-6.
Tamoxifen-induced fluorescence was used as a marker of hormone receptors in breast tumor cytology. Patients receiving Tamoxifen were compared to patients without such a therapy. Only those receiving this treatment showed fluorescence in their malignant cells. Moreover, in this group, such a fluorescence was noticed only in those patients with hormonal receptors in their tumor cells and not in the patients without estrogen and progesterone receptors. Such a technique seems to be a good method for predicting response to hormonal therapy.
他莫昔芬诱导的荧光被用作乳腺肿瘤细胞学中激素受体的标志物。将接受他莫昔芬治疗的患者与未接受这种治疗的患者进行比较。只有接受这种治疗的患者在其恶性细胞中显示出荧光。此外，在这组患者中，仅在肿瘤细胞中有激素受体的患者中观察到这种荧光，而在没有雌激素和孕激素受体的患者中未观察到。这种技术似乎是预测激素治疗反应的一种好方法。
