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兆伏电子束疗法治疗耳廓基底细胞癌和鳞状细胞癌。

Megavoltage electron beam therapy in the treatment of basal and squamous cell carcinomata of the pinna.

作者信息

Hunter R D, Pereira D T, Pointon R C

出版信息

Clin Radiol. 1982 May 3;33(3):341-5. doi: 10.1016/s0009-9260(82)80285-7.

Abstract

Kilovoltage X-ray therapy has considerable limitations when trying to obtain good functional results in patients with skin carcinomas arising on the pinna. Megavoltage electron beams with their better quality of radiation and homogeneous dose distribution have been recognised to have theoretical advantages. Forty-three patients with basal and squamous cell carcinomata arising on the pinna were treated radically using a 10 MeV electron beam. The technique and dosage are described and discussed. Primary cancer control with retention of the pinna was achieved in 34 patients. Salvage pinnectomy was performed in four patients for recurrence and one patient for radiation necrosis. Two patients with large primary tumours failed to resolve and died of their disease. The advantages for the patient of the policy of primary radical electron mean therapy are discussed.

摘要

在试图让耳廓出现皮肤癌的患者获得良好功能结果时,千伏X射线治疗有相当大的局限性。兆伏电子束具有更好的辐射质量和均匀的剂量分布,已被认为具有理论优势。43例耳廓出现基底细胞癌和鳞状细胞癌的患者接受了10 MeV电子束根治性治疗。描述并讨论了该技术和剂量。34例患者实现了耳廓保留的原发性癌症控制。4例患者因复发接受了挽救性耳廓切除术,1例患者因放射性坏死接受了该手术。2例原发性肿瘤较大的患者未能治愈,死于疾病。讨论了原发性根治性电子束治疗策略对患者的优势。

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