Palkovits M, Eskay R L, Brownstein M J
Endocrinology. 1982 May;110(5):1526-8. doi: 10.1210/endo-110-5-1526.
The topographical distribution of fibers containing TRH that run to the median eminence has been investigated by RIA of TRH after hypothalamic surgical transections in rats. Anterolateral or lateral cuts bilaterally transecting fibers at the caudal edge of the optic chiasm (lateral retrochiasmatic area) diminish TRH levels in the median eminence by 95% and 73%, respectively. Paramedian cuts are ineffective. These results suggest that TRH fibers reach the medial basal hypothalamus from an anterolateral direction just as several other classes of peptide containing fibers do.
通过对大鼠下丘脑进行手术横断后，利用促甲状腺激素释放激素（TRH）的放射免疫分析（RIA），研究了投射至正中隆起的含TRH纤维的拓扑分布。双侧在前连合交叉尾缘（外侧视交叉后区）进行前外侧或外侧切口切断纤维，分别使正中隆起处的TRH水平降低95%和73%。旁正中切口则无效。这些结果表明，TRH纤维如同其他几类含肽纤维一样，从前外侧方向到达下丘脑内侧基底部。
