β-丙氨酸和α-L-丙氨酸抑制自发性高血压大鼠的探究活动。
beta-Alanine and alpha-L-alanine inhibit the exploratory activity of spontaneously hypertensive rats.
作者信息
Lilequist R, Paasonen M K, Solatunturi E
出版信息
Experientia. 1982 Mar 15;38(3):379-80. doi: 10.1007/BF01949405.
PMID:6804258
Abstract
1% beta-alanine and alpha-L-alanine, when given for 7 days as the only drinking fluid, inhibited the exploratory activity of adult male spontaneously-hypertensive rats (SHR) but not that of the normotensive Wistar-Kyoto rats (WKR). beta-Alanine decreased the taurine level in the liver of both strains and in the platelets of SHR. alpha-Alanine decreased the taurine level in the liver of WKR and in the platelets of SHR.
摘要
1%的β-丙氨酸和α-L-丙氨酸作为唯一的饮水给予7天，可抑制成年雄性自发性高血压大鼠（SHR）的探索活动，但对正常血压的Wistar-Kyoto大鼠（WKR）则无此作用。β-丙氨酸降低了两种品系大鼠肝脏以及SHR血小板中的牛磺酸水平。α-丙氨酸降低了WKR肝脏以及SHR血小板中的牛磺酸水平。
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