Cannon S R, Richards K L, Rollwitz W T
J Clin Ultrasound. 1982 Mar;10(3):101-7. doi: 10.1002/jcu.1870100303.
Pulsed Doppler echocardiography and digital Fourier analysis were utilized to examine flow distal to the aortic valve and to quantify aortic stenosis. A graphic index of parameters derived from velocity spectrum patterns generated by Fourier analysis was regressed against mean systolic pressure gradients in 21 adults with clinical evidence of aortic stenosis who underwent catheterization studies and five normal adults (r = .82). Correlation improved in the absence of regurgitation (r = .92). Sensitivity for detecting gradients greater than 30 mmHg was 86%; specificity was 90%. Doppler spectral analysis shows promise in alleviating the need for many invasive studies.
采用脉冲多普勒超声心动图和数字傅里叶分析技术，对主动脉瓣远端血流进行检测，并对主动脉瓣狭窄进行量化分析。对21例有主动脉瓣狭窄临床证据且接受了心导管检查的成人以及5例正常成人，将由傅里叶分析生成的速度频谱模式得出的参数图形指数与平均收缩压梯度进行回归分析（r = 0.82）。在无反流情况下，相关性有所提高（r = 0.92）。检测大于30 mmHg梯度的敏感性为86%；特异性为90%。多普勒频谱分析有望减少许多侵入性检查的需求。
