Schwartz A R, Leddy A L
Obstet Gynecol. 1982 Mar;59(3):394-8.
The association of diabetes insipidus with postpartum hypopituitarism is unusual. This report presents a patient with both conditions. Evidence pointing to the pathogenesis of the diabetes insipidus is discussed. This case and selected others illustrate the wide spectrum in the severity of diabetes insipidus encountered in postpartum hypopituitarism, as well as the masking of symptoms caused by concomitant glucocorticoid insufficiency. Histopathologic and experimental evidence suggests that patients with hypopituitarism occurring postpartum might also display mild diabetes insipidus if challenged with antidiuretic stimuli. Diabetes insipidus may be a feature of postpartum hypopituitarism that is infrequently recognized.
尿崩症与产后垂体功能减退相关的情况并不常见。本报告介绍了一位同时患有这两种病症的患者。文中讨论了指向尿崩症发病机制的证据。该病例及其他一些病例表明，产后垂体功能减退时尿崩症的严重程度范围很广，同时糖皮质激素不足所导致的症状也会掩盖尿崩症症状。组织病理学和实验证据表明，产后发生垂体功能减退的患者若受到抗利尿刺激，也可能表现出轻度尿崩症。尿崩症可能是产后垂体功能减退的一个特征，但却很少被认识到。
