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人类伤寒热的免疫学研究。II 细胞介导的免疫反应。

Immunological study of typhoid fever in man. II Cell-mediated immune response.

作者信息

Sangpetchsong V, Tharavanij S

出版信息

Southeast Asian J Trop Med Public Health. 1981 Sep;12(3):357-63.

PMID:6805078
Abstract

The development of cell-mediated immune response to lipopolysaccharide and Barber protein from Salmonella typhi was investigated in patients suffering from typhoid fever. The cell-mediated immunity as measured by the leukocyte adherence inhibition test, was demonstrable in 77% of patients with typhoid fever but only in 5.6% of healthy controls. It was found that cell-mediated immune response appeared after the first week of illness and persisted for at least 4 weeks. The time course development of cell-mediated immune response and humoral immune response was correlated but the magnitude of each response was independent on one another.

摘要

对伤寒热患者针对伤寒沙门氏菌脂多糖和巴伯蛋白的细胞介导免疫反应的发展进行了研究。通过白细胞黏附抑制试验测量的细胞介导免疫,在77%的伤寒热患者中可检测到,但在健康对照者中仅为5.6%。发现细胞介导免疫反应在疾病第一周后出现,并持续至少4周。细胞介导免疫反应和体液免疫反应的时间进程发展相关,但每种反应的程度相互独立。

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