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[用精神安定药对行为障碍儿童和青少年进行长期治疗]

[Long-term treatment with psychoverlan in children and adolescents with behavior disorders].

作者信息

Heinze H

出版信息

Fortschr Med. 1978 Aug 24;96(32).

PMID:680616
Abstract

Numerous pharmacological and clinical long-term studies on mono-magnesium-L-glutamate-hydrobromide. H2O were reason to undertake another trial in adolescents with reactive behavioral abnormalities. The aim of the study was to assess the effecacy of Psychoverlan in abolishing or improving these symptoms and to reveal any possible drug-induced side effects. In a long-term study 19 young females were treated with Psychoverlan capsules or syrup for an average of 11.4 months. Intolerance phenomena and side-effects were not seen. It was even decided to increase the standard dose. None of the patients developed brominism or bromine intoxication. The general state of health of 13 of the 19 subjects was improved by the harmonizing effect of the drug on psychic and vegetative functions. Tiredness and somnolence were not observed.

摘要

关于一水合L-谷氨酸氢溴酸镁进行了大量药理学和临床长期研究。这些研究促使我们对患有反应性行为异常的青少年开展另一项试验。该研究的目的是评估精神安定药在消除或改善这些症状方面的疗效,并揭示任何可能的药物诱发副作用。在一项长期研究中,19名年轻女性接受了精神安定药胶囊或糖浆治疗,平均治疗时间为11.4个月。未观察到不耐受现象和副作用。甚至决定增加标准剂量。没有患者出现溴中毒或溴 intoxication。19名受试者中有13人的总体健康状况因药物对精神和植物神经功能的协调作用而得到改善。未观察到疲劳和嗜睡现象。

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