Leigh B, Schalet A P, Paradi E
Mutat Res. 1982 Feb 22;92(1-2):133-8. doi: 10.1016/0027-5107(82)90217-2.
Neutrons and X-rays were used to induce mutations at the yellow, white, vermilion and forked loci of Drosophila melanogaster by irradiation of spermatozoa in males. The mutations were characterized for the presence and location of simultaneously induced rearrangements and recessive lethal mutations. F1 females carrying induced visible mutations were identified, described and tested for fertility. The data are given in this paper. The proportions of mutants at the 4 loci, the ratios of whole-body: mosaic mutations, and the fertility of the mutant-carrying F1 females were similar for both types of radiation. Differences were observed between the frequencies of induced visible mutations and the rates of coincident visible and lethal induction. Although the analysis of the mutant chromosomes has not yet been completed, our data can be interpreted as providing confirmation that there are qualitative differences between the genetic effects of neutrons and X-rays.
通过照射雄性果蝇的精子,利用中子和X射线在黑腹果蝇的黄色、白色、朱红色和叉毛位点诱导突变。对同时诱导的重排和隐性致死突变的存在和位置进行了突变特征分析。鉴定、描述并测试了携带诱导可见突变的F1雌性果蝇的生育能力。本文给出了相关数据。两种辐射在4个位点的突变体比例、全身突变与嵌合突变的比率以及携带突变的F1雌性果蝇的生育能力相似。在诱导可见突变的频率与同时出现的可见突变和致死诱导率之间观察到了差异。虽然对突变染色体的分析尚未完成,但我们的数据可以解释为证实了中子和X射线的遗传效应存在质的差异。