Bakke J E, Bergman A L, Larsen G L
Science. 1982 Aug 13;217(4560):645-7. doi: 10.1126/science.6806905.
Carbon-14-labeled 2,4',5-trichlorobiphenyl was found to be metabolized by the mercapturic acid pathway to metabolites that are excreted in bile. About 57 percent of the carbon-14 was excreted in the bile; 30 to 35 percent was present as mercapturic acid pathway metabolites. Mercapturic acid was also isolated from the urine (0.3 percent of the dose).
碳 - 14标记的2,4',5 - 三氯联苯经巯基尿酸途径代谢为经胆汁排泄的代谢物。约57%的碳 - 14经胆汁排泄;30%至35%以巯基尿酸途径代谢物形式存在。尿液中也分离出了巯基尿酸(占剂量的0.3%)。