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Chronic tubulointerstitial nephritis and wasting disease in marmosets (Callithrix jacchus).

作者信息

Brack M, Rothe H

出版信息

Vet Pathol. 1981 Apr;18(Suppl 6):45-54. doi: 10.1177/0300985881018s0605.

DOI:10.1177/0300985881018s0605
PMID:6806966
Abstract

Six marmosets (Callithrix jacchus), 20 months to 16 years old, died from a disease characterized by weakness and paralysis of the hind legs, weight lose, anemia and transient diarrhea. The lesions most prominent at necropsy were subacute to chronic tubulointerstitial nephritis, subacute to chronic pancreatitis, and generalized hemosiderosis. Chronic protein deficiency is believed to be the underlying pathogenic mechanism, since the diet contained no more than 15% animal protein during the last two years, and increasing the amount of protein was accompanied by disappearance of the syndrome.

摘要

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