von Konow L, Nord C E, Nordenram A
Int J Oral Surg. 1981 Oct;10(5):313-22. doi: 10.1016/s0300-9785(81)80027-0.
The bacteriology of 57 dentoalveolar infections was studied using optimal techniques to collect, transport and process specimens. There was an average of 4 bacterial species per specimen, and only 1/3 of the specimens held aerobes. Among the aerobic bacteria, streptococci dominated and among the anaerobes the Gram-negative rods, Bacteroides ruminicola and Fusobacterium nucleatum, were most frequently isolated followed by Gram-positive cocci, in particular Streptococcus intermedius. All aerobic isolates were resistant to penicillins but sensitive to clindamycin and tinidazole. The other anaerobic isolates were sensitive to penicillins but showed varying susceptibility to erythromycin and doxycycline. Tinidazole was effective against all anaerobic Gram-negative rods. The presence of volatile fatty acids in pus from dentoalveolar infections was found to be of presumptive value for the diagnosis of anaerobic infections. Direct gas-liquid chromatographic analysis of pus is recommended as a routine procedure for preliminary diagnosis of anaerobic dentoalveolar infections.
采用优化技术收集、运送和处理标本，对57例牙槽感染的细菌学进行了研究。每个标本平均有4种细菌，仅1/3的标本含有需氧菌。在需氧菌中，链球菌占主导地位；在厌氧菌中，革兰氏阴性杆菌、瘤胃拟杆菌和具核梭杆菌最常分离出来，其次是革兰氏阳性球菌，尤其是中间型链球菌。所有需氧菌分离株对青霉素耐药，但对克林霉素和替硝唑敏感。其他厌氧菌分离株对青霉素敏感，但对红霉素和强力霉素的敏感性各不相同。替硝唑对所有厌氧革兰氏阴性杆菌均有效。发现牙槽感染脓液中挥发性脂肪酸的存在对厌氧菌感染的诊断具有推定价值。建议将脓液的直接气-液色谱分析作为牙槽厌氧菌感染初步诊断的常规程序。
