哌仑西平对毒蕈碱受体的阻断作用：对人体催乳素分泌的影响。
Muscarinic receptor blockade by pirenzepine: effect on prolactin secretion in man.
作者信息
Masala A, Alagna S, Devilla L, Rovasio P P, Rassa S, Faedda R, Satta A
出版信息
J Endocrinol Invest. 1982 Jan-Feb;5(1):53-5. doi: 10.1007/BF03350483.
PMID:6808052
Abstract
The effect of pirenzepine, a muscarinic receptor blocker which does not cross the blood brain barrier, on basal and TRH-stimulated prolactin (PRL) secretion in normal subjects was studied. Administration of 75 mg oral pirenzepine had no effects on prolactin levels in male subjects whereas it significantly reduced prolactin in females. No effect on TRH induced prolactin secretion was observed.
摘要
研究了一种不能穿过血脑屏障的毒蕈碱受体阻滞剂哌仑西平对正常受试者基础及促甲状腺激素释放激素（TRH）刺激的催乳素（PRL）分泌的影响。口服75毫克哌仑西平对男性受试者的催乳素水平无影响，而对女性则显著降低催乳素水平。未观察到对TRH诱导的催乳素分泌有影响。
Zotero 插件