Crabbé J, Nagel W
Pflugers Arch. 1982 Apr;393(2):130-2. doi: 10.1007/BF00582934.
Toad skin exposed overnight to aldosterone, was examined by means of microelectrodes before and after addition of glucose to the incubation fluid in 7 instances. Glucose addition led with minutes to epithelial cell hyperpolarization associated with increases of conductances at both cell borders, the increase being twice as large (in relative terms) at the basolateral border as at the apical one. Since glucose had no effect on untreated preparations, these observations represent another argument for aldosterone influencing target cells in a way that is not restricted to increased apical conductance.
在7个实例中，用微电极对蟾蜍皮肤进行了检查，这些蟾蜍皮肤在醛固酮作用下暴露过夜，在向孵育液中添加葡萄糖之前和之后进行了检查。添加葡萄糖几分钟后，上皮细胞发生超极化，同时细胞两侧的电导增加，基底外侧边界的增加幅度（相对而言）是顶端边界的两倍。由于葡萄糖对未处理的标本没有影响，这些观察结果为醛固酮以不限于增加顶端电导的方式影响靶细胞提供了另一个论据。
