Bonifas P, Hagenmuller M P, Habrard M, Dondey M
Rev Electroencephalogr Neurophysiol Clin. 1981 Dec;11(3-4):474-80. doi: 10.1016/s0370-4475(81)80088-3.
The authors studied 111 children whose EEG showed paroxysmal foci on the lateral areas of the skull, often on the rolandic and temporal areas, but also on occipital, parietal and frontal areas. In 60% of the cases there was no clinical epileptic manifestation. In 25% of the cases those foci were responsible for epileptic seizures with good prognosis; in 15% of the cases they were associated with other epileptogenic processes responsible for epileptic fits of unfavorable evolution. The past history of these children had been studied in particular: hyperthermic convulsions and lateralisation difficulties were very frequent, but organic lesions were also found, which, although they did not seem to be directly responsible for the foci, were related to the organic lesion by a reactional or 'functional' factor.
作者研究了111名儿童,这些儿童的脑电图显示颅骨外侧区域存在阵发性病灶,通常位于中央沟和颞叶区域,但也见于枕叶、顶叶和额叶区域。60%的病例无临床癫痫表现。25%的病例中,这些病灶导致癫痫发作,预后良好;15%的病例中,它们与其他致痫过程相关,这些过程导致癫痫发作且病情进展不利。对这些儿童的既往史进行了特别研究:热性惊厥和偏侧化困难非常常见,但也发现了器质性病变,尽管这些病变似乎并非病灶的直接原因,但通过反应性或“功能性”因素与器质性病变相关。