Samson-Dollfus D, Szeibert J, Parain D, Senant J, Menard J F
Rev Electroencephalogr Neurophysiol Clin. 1981 Dec;11(3-4):425-30. doi: 10.1016/s0370-4475(81)80081-0.
Between 1955 and 1970 recordings were made from 125 children aged 1-36 months who had had a first epileptic seizure (non-hyperthermic). 100 of these children were followed up for from 5 to 20 years: 35 had had their first seizure before 1 year of age and 65 between the age of 1 and 3. Hypsarrythmia was more frequent under 1 year of age, whereas short diffuse spike and wave bursts were observed only after 1 year. However, localized spikes, asymmetrical or slow tracings as well as normal tracings were observed in both groups, without significant difference. A fatal outcome is more frequent when the first seizure took place before the age of 1 year. However, in our sample the intellectual development of the surviving children does not depend on the time of the first seizure. In any case the prognosis is unfavorable, since only 31 of the children followed up developed normally.
在1955年至1970年间,对125名1至36个月大首次发生癫痫发作(非热性)的儿童进行了记录。其中100名儿童接受了5至20年的随访:35名儿童在1岁前首次发作,65名儿童在1至3岁之间首次发作。婴儿痉挛症在1岁以下更为常见,而短程弥漫性尖波和棘波暴发仅在1岁后观察到。然而,两组均观察到局限性尖波、不对称或慢波描记以及正常描记,无显著差异。首次发作发生在1岁前时,致命结局更为常见。然而,在我们的样本中,存活儿童的智力发育并不取决于首次发作的时间。无论如何,预后都不理想,因为在接受随访的儿童中只有31名发育正常。