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献血者血清丙氨酸氨基转移酶:活性分布及表型的影响

Serum alanine aminotransferase in blood donors: activity distribution and effect of phenotype.

作者信息

Savage B, Sayers M H, Giblett E R

出版信息

Transfusion. 1982 Jul-Aug;22(4):298-9. doi: 10.1046/j.1537-2995.1982.22482251212.x.

DOI:10.1046/j.1537-2995.1982.22482251212.x
PMID:6808720
Abstract

Alanine aminotransferase (ALT) phenotype and serum activities were determined in 200 random volunteer blood donors. Serum enzyme activities were not significantly affected by the ALT phenotype (p greater than 0.1). Studies on 500 random volunteer blood donors showed significant differences in serum ALT levels between male and female donors (p less than 0.001). Elevated serum ALT levels were more commonly found in male donors; the frequency of male donors with levels of 45 IU/l or higher was 2.5 percent compared with 0.9 percent in female donors. The frequency of donors with serum ALT levels of 80 IU/l or higher was 0.6 percent of the total donor population sampled.

摘要

对200名随机抽取的无偿献血者测定了丙氨酸氨基转移酶(ALT)表型和血清活性。血清酶活性不受ALT表型的显著影响(p>0.1)。对500名随机抽取的无偿献血者的研究表明,男性和女性献血者的血清ALT水平存在显著差异(p<0.001)。血清ALT水平升高在男性献血者中更为常见;ALT水平在45 IU/l及以上的男性献血者频率为2.5%,而女性献血者为0.9%。血清ALT水平在80 IU/l及以上的献血者频率占抽样总献血人群的0.6%。

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