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[鸡肠上皮细胞中乳糜微粒的起源与转运]

[The origin and transport of chylomicrons in enterocytes in chickens].

作者信息

Holman J

出版信息

Vet Med (Praha). 1982 May;27(5):295-308.

PMID:6808756
Abstract

After peroral administration of sunflower oil to chick old 14 to 23 days, the rise and passage of chylomicrons were studied electronoptically in the enterocytes of the small intestine. Enterocytes resynthetize the absorbed monoglycerides and fatty acids into neutral fat in the profiles of smooth endoplasmic reticulum and in multivesicular corpuscles in the form of chylomicrons and loose cytoplasmic fat drops in their apical part. The finishing and transport of chylomicrons in the enterocyte are the result of the activity of granular endoplasmic reticulum and the Golgi apparatus. Exocytose carries chylomicrons from enterocytes to intercellular space of the epithelium from where they pass the basal membrane of the epithelium and then, carried by pinocytose, they pass into the lumen of the blood and chyle capillaries. No morphological manifestations of fat absorption in the other cell types of intestinal epithelium (goblet cells, argyrophil cells and intraepithelial lymphocytes) were demonstrated.

摘要

给14至23日龄的雏鸡经口投喂向日葵油后,用电镜观察小肠肠上皮细胞中乳糜微粒的生成及转运过程。肠上皮细胞将吸收的甘油单酯和脂肪酸在内质网滑面内质网的轮廓以及多囊小体中重新合成中性脂肪,形成乳糜微粒,并在其顶端部分形成松散的细胞质脂滴。乳糜微粒在肠上皮细胞中的完成和转运是粗面内质网和高尔基体活动的结果。胞吐作用将乳糜微粒从肠上皮细胞转运到上皮细胞间间隙,然后它们穿过上皮细胞的基底膜,再通过胞饮作用进入血液和乳糜管腔。在肠道上皮的其他细胞类型(杯状细胞、嗜银细胞和上皮内淋巴细胞)中未发现脂肪吸收的形态学表现。

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