Mörl M
Z Gerontol. 1982 Mar-Apr;15(2):113-7.
Although infectious hepatitis (IH) is, at the present time, predominantly a disease of adolescence and young adulthood, when it does occur in advanced age, it is associated with a higher level of mortality due to fulminant hepatitis, and with a more frequently chronic, subicteric and anicteric course. The reasons for this are to be found in a greater viral persistence, with concomitant lowering of the immune defences, secondary diseases, prior diseases of the liver, drug and alcohol abuse. A particularly unfavourable effect on the prognosis is ascribed to the use of corticosteroids in the acute phase of the disease.
尽管目前感染性肝炎(IH)主要是青少年和青年期的疾病,但在老年时发病,因暴发性肝炎导致的死亡率更高,且病程更常为慢性、亚黄疸型和无黄疸型。其原因在于病毒持续存在时间更长,同时免疫防御功能降低、有继发性疾病、既往肝脏疾病、药物和酒精滥用。疾病急性期使用皮质类固醇被认为对预后有特别不利的影响。