Horak W
Aktuelle Gerontol. 1983 Nov;13(6):214-6.
Elderly people rarely develop hepatitis A, because of their acquired immunity, but they are more exposed to hepatitis-B and -nonAnonB infections. The course of viral hepatitis is usually more severe and more prolonged, the mortality of fulminant hepatitis is higher, and the risk of developing chronic hepatitis B is increased. There exists an association between chronic hepatitis B virus infection, old age, and the incidence of hepatoma. Exposed elderly persons should be vaccinated against hepatitis B but it might be necessary to give them additional booster doses in order to achieve sufficient antibody production.
老年人由于获得性免疫,很少感染甲型肝炎,但他们更容易感染乙型肝炎和非甲非乙型肝炎。病毒性肝炎的病程通常更严重、更漫长,暴发性肝炎的死亡率更高,发生慢性乙型肝炎的风险增加。慢性乙型肝炎病毒感染、老年与肝癌发病率之间存在关联。接触过病毒的老年人应接种乙型肝炎疫苗,但可能需要给他们额外接种加强针,以产生足够的抗体。