Osuna O, Edds G T, Simpson C F
Am J Vet Res. 1982 Aug;43(8):1395-400.
The effects of feeding dietary cadmium (83 micrograms/g of diet) to young pigs on the distributions of copper, iron, and zinc in urine samples and in kidney, liver, and muscle tissues was determined. The diet with added Cd resulted in renal and hepatic tissue concentrations of 42.90 +/- 10.57 micrograms/g and 7.90 +/- 2.37 micrograms/g, respectively, at the 40th day of the experiment. Iron was found to decrease at the same time, which predisposed to the anemic condition of these pigs. The feeding of dietary CD to pigs prevented extensive fatty hepatocytic infiltration and severe jaundice, but not hydropic degeneration induced by aflatoxin B1. Cadmium increased the toxicity of warfarin with severe lameness, subcutaneous hematomas in the ventral surface of the neck, and death.
研究了给幼猪喂食含镉日粮（83微克/克日粮）对尿液样本以及肾脏、肝脏和肌肉组织中铜、铁和锌分布的影响。在实验第40天时，添加镉的日粮分别导致肾脏和肝脏组织中镉的浓度为42.90±10.57微克/克和7.90±2.37微克/克。同时发现铁含量降低，这使这些猪易患贫血症。给猪喂食含镉日粮可防止广泛的脂肪性肝细胞浸润和严重黄疸，但不能预防黄曲霉毒素B1诱导的水样变性。镉增加了华法林的毒性，导致严重跛行、颈部腹面皮下血肿以及死亡。
