Brennan M F, Burt M E
Cancer Treat Rep. 1981;65 Suppl 5:67-78.
The methods of examining nitrogen metabolism in cancer-bearing humans are examined with specific examples. The major nutritional effect of cancer on the host is lean tissue and caloric reserve dissolution, with increased total body water. It seems clear that gluconeogenesis from amino acids can be suppressed by exogenous substrate. With appropriate nutritional repletion, protein catabolism can be suppressed and synthesis stimulated.
本文通过具体实例探讨了检测癌症患者氮代谢的方法。癌症对宿主的主要营养影响是瘦组织和热量储备的分解，同时全身水分增加。显然，外源性底物可抑制氨基酸的糖异生作用。通过适当的营养补充，可抑制蛋白质分解代谢并刺激其合成。
