Agarwal J L, Shukla N, Tandon G S
Indian J Physiol Pharmacol. 1978 Jan-Mar;22(1):53-60.
Fifteen healthy stray dogs of both sexes were employed in the present study. The effect of distension of right and left atrial appendages with normal saline was observed on heart rate and blood pressure under different situations. It has been found that distension of either appendages separately or simultaneously invariably evoked tachycardia without any appreciable change in blood pressure. Increase in heart rate was found to be of a same magnitude with 5 ml normal saline in both the atrial appendages. However, a higher response was obtained with 10 ml normal saline distension in case of right atrial appendage as compared to left one. Increase in the extent of distension causes more significant response, the receptors of which are stimulated and may be allied to stretch receptors. It is contended that tachycardia could be a reflex effect which is abolished by vagotomy. It is further contended that either afferent, efferent or both pathways exist in the vagi.
本研究选用了15只健康的雌雄 stray dogs。观察了在不同情况下用生理盐水扩张右心耳和左心耳对心率和血压的影响。已发现单独或同时扩张任一心耳均能诱发心动过速,而血压无明显变化。在两个心耳中,用5毫升生理盐水扩张时,心率增加幅度相同。然而,与左心耳相比,右心耳用10毫升生理盐水扩张时反应更高。扩张程度增加会引起更显著的反应,其受体受到刺激,可能与牵张受体有关。有人认为心动过速可能是一种反射效应,迷走神经切断术可消除这种效应。进一步有人认为迷走神经中存在传入、传出或两者兼有的通路。