Washida H, Jinno H, Fushimi N, Watanabe H
Cryobiology. 1982 Jun;19(3):237-41. doi: 10.1016/0011-2240(82)90149-3.
Pituitary gland response to releasing hormone using the LH-RH loading test before and 4 weeks after cryosurgery of the prostate was investigated in eight patients with advanced prostatic carcinoma. In pre- and postoperative comparisons of all patients, there were no significant differences detected before and after surgery. But pituitary response to the releasing hormone was compared before and after the surgery in each of the patients; in one, depression and facilitation of FSH and LH secretion, respectively, were observed and there was a variation in the response of gonadotropin in each patient. Although the number of observable patients is still too low to draw any definite conclusions from the test results, one possible interpretation is that cryosurgery of the prostate may influence hormonal secretion from the pituitary gland.
对8例晚期前列腺癌患者在前列腺冷冻手术前及术后4周，使用促黄体激素释放激素（LH-RH）负荷试验研究垂体对释放激素的反应。在所有患者术前和术后的比较中，手术前后未检测到显著差异。但对每位患者手术前后垂体对释放激素的反应进行了比较；其中1例分别观察到促卵泡激素（FSH）和促黄体生成素（LH）分泌的抑制和促进，且每位患者促性腺激素的反应存在差异。尽管可观察的患者数量仍然太少，无法从测试结果中得出任何明确结论，但一种可能的解释是前列腺冷冻手术可能会影响垂体的激素分泌。
