2-乙酰氨基芴和N-羟基-2-乙酰氨基芴对环氧化物水解酶、细胞色素P-450b和NADPH-细胞色素c（P-450）氧化还原酶信使核糖核酸细胞水平的影响。 - Suppr

Suppr

超能文献

Effects of 2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene on the cellular levels of epoxide hydratase, cytochrome P-450b, and NADPH-cytochrome c (P-450) oxidoreductase messenger ribonucleic acids.

作者信息

Gonzalez F J, Samore M, McQuiddy P, Kasper C B

出版信息

J Biol Chem. 1982 Sep 25;257(18):11032-6.

PMID:6809765

Abstract

摘要

相似文献

Effects of 2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene on the cellular levels of epoxide hydratase, cytochrome P-450b, and NADPH-cytochrome c (P-450) oxidoreductase messenger ribonucleic acids.2-乙酰氨基芴和N-羟基-2-乙酰氨基芴对环氧化物水解酶、细胞色素P-450b和NADPH-细胞色素c（P-450）氧化还原酶信使核糖核酸细胞水平的影响。

J Biol Chem. 1982 Sep 25;257(18):11032-6.

Transcriptional regulation of rat liver epoxide hydratase, NADPH-Cytochrome P-450 oxidoreductase, and cytochrome P-450b genes by phenobarbital.

J Biol Chem. 1983 Jul 10;258(13):8081-5.

Interaction of epoxide hydrolase with itself and other microsomal proteins.环氧化物水解酶与自身及其他微粒体蛋白的相互作用。

Arch Biochem Biophys. 1982 May;215(2):462-77. doi: 10.1016/0003-9861(82)90105-9.

A preliminary characterization of drug-metabolizing systems in preneoplastic nodules from the livers of rats receiving 2-acetylaminofluorene in their diet.对饮食中摄入2-乙酰氨基芴的大鼠肝脏癌前结节中药物代谢系统的初步表征。

Acta Chem Scand B. 1981;35(3):219-20. doi: 10.3891/acta.chem.scand.35b-0219.

Induction of different isozymes of cytochrome P-450 and of microsomal epoxide hydrolase in rat liver by 2-acetylaminofluorene and structurally related compounds.2-乙酰氨基芴及结构相关化合物对大鼠肝脏细胞色素P-450不同同工酶和微粒体环氧化物水解酶的诱导作用。

Eur J Biochem. 1986 Jan 2;154(1):125-34. doi: 10.1111/j.1432-1033.1986.tb09367.x.

Induction of the hepatic mixed-function oxidase system by synthetic glucocorticoids. Transcriptional and post-transcriptional regulation.合成糖皮质激素对肝脏混合功能氧化酶系统的诱导作用。转录和转录后调控。

J Biol Chem. 1987 Jan 5;262(1):326-32.

Cloning of DNA complementary to rat liver NADPH-cytochrome c (P-450) oxidoreductase and cytochrome P-450b mRNAs. Evidence that phenobarbital augments transcription of specific genes.大鼠肝脏NADPH-细胞色素c（P-450）氧化还原酶和细胞色素P-450b信使核糖核酸互补DNA的克隆。苯巴比妥增强特定基因转录的证据。

J Biol Chem. 1982 May 25;257(10):5962-8.

Trans-stilbene oxide: a selective inducer of rat liver epoxide hydratase.反式氧化芪：大鼠肝脏环氧化物水解酶的选择性诱导剂。

Mol Pharmacol. 1978 Sep;14(5):834-47.

Turnover of membrane proteins: kinetics of induction and degradation of seven forms of rat liver microsomal cytochrome P-450, NADPH-cytochrome P-450 reductase, and epoxide hydrolase.膜蛋白的周转：大鼠肝脏微粒体细胞色素P-450七种形式、NADPH-细胞色素P-450还原酶和环氧水解酶的诱导和降解动力学。

Arch Biochem Biophys. 1984 Nov 15;235(1):86-96. doi: 10.1016/0003-9861(84)90257-1.

Purification of cytochrome P-450, NADPH-cytochrome P-450 reductase, and epoxide hydratase from a single preparation of rat liver microsomes.从大鼠肝脏微粒体的单一制剂中纯化细胞色素P-450、NADPH-细胞色素P-450还原酶和环氧化物水合酶。

Arch Biochem Biophys. 1980 Dec;205(2):365-79. doi: 10.1016/0003-9861(80)90119-8.

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BMC Complement Altern Med. 2017 Jan 18;17(1):56. doi: 10.1186/s12906-017-1567-9.

Genetic enhancement of microsomal epoxide hydrolase improves metabolic detoxification but impairs cerebral blood flow regulation.微粒体环氧化物水解酶的基因增强可改善代谢解毒，但会损害脑血流调节。

Arch Toxicol. 2016 Dec;90(12):3017-3027. doi: 10.1007/s00204-016-1666-2. Epub 2016 Feb 2.

The role of individual susceptibility in cancer burden related to environmental exposure.个体易感性在与环境暴露相关的癌症负担中的作用。

Environ Health Perspect. 1996 May;104 Suppl 3(Suppl 3):569-77. doi: 10.1289/ehp.96104s3569.

A bipartite suppressor: conjunction of two distinct factor-binding sites is essential for down-regulation in rat epoxide hydrolase gene expression.一种双组分抑制因子：两个不同因子结合位点的结合对于大鼠环氧化物水解酶基因表达的下调至关重要。

Mol Cell Biol. 1992 Oct;12(10):4496-502. doi: 10.1128/mcb.12.10.4496-4502.1992.

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