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草花粉抗原与玉米花粉抗原之间的交叉反应性。

Cross-reactivity between grass and corn pollen antigens.

作者信息

Kalveram K J, Forck G

出版信息

Int Arch Allergy Appl Immunol. 1978;57(6):549-53. doi: 10.1159/000232151.

DOI:10.1159/000232151
PMID:680992
Abstract

Analogous reactions of grass and corn pollen extracts in skin tests on patients suffering from pollinosis might suggest an antigenic relationship between grass and corn pollens. This problem was studied using the RAST inhibition test. Tests were performed with cellulose discs labelled with commercial skin test extracts containing grass, rye, wheat, barley, oat and maize pollens. Different mutual inhibitions were measured showing various grades of antigenic relationship. Only grass pollen antigens could strongly inhibit all other antigen-antibody reactions. Thus, we suppose that the investigated grass pollen extract also contains all antigens typical of corn pollen. Therefore, exclusive use of this extract seems to be possible in diagnosis and perhaps therapy of combined grass and corn pollen allergy.

摘要

在花粉症患者身上进行皮肤试验时,草和玉米花粉提取物的类似反应可能表明草花粉和玉米花粉之间存在抗原关系。本研究使用放射性变应原吸附抑制试验(RAST抑制试验)来探究这一问题。试验采用纤维素圆盘,圆盘上标记有含草、黑麦、小麦、大麦、燕麦和玉米花粉的商业皮肤试验提取物。测量得到不同的相互抑制情况,显示出不同程度的抗原关系。只有草花粉抗原能强烈抑制所有其他抗原 - 抗体反应。因此,我们推测所研究的草花粉提取物也包含玉米花粉的所有典型抗原。所以,在草花粉和玉米花粉联合过敏的诊断甚至治疗中,似乎有可能单独使用这种提取物。

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1
Cross-reactivity between grass and corn pollen antigens.草花粉抗原与玉米花粉抗原之间的交叉反应性。
Int Arch Allergy Appl Immunol. 1978;57(6):549-53. doi: 10.1159/000232151.
2
[Studies on antigenic relationship between grass- and cult. rye pollens by skin-test, RAST and RAST-inhibition-test in patients with pollinosis (author's transl)].[通过皮肤试验、放射变应原吸附试验(RAST)及RAST抑制试验对花粉症患者进行草花粉与栽培黑麦花粉抗原关系的研究(作者译)]
Arch Dermatol Res (1975). 1977 Oct 27;260(1):17-27. doi: 10.1007/BF00558010.
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Immunobiology of grass pollen allergens.草花粉过敏原的免疫生物学
Curr Allergy Asthma Rep. 2005 Sep;5(5):381-7. doi: 10.1007/s11882-005-0011-2.
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Cross-reactivity of plant and animal allergens.植物和动物过敏原的交叉反应性。
Clin Rev Allergy Immunol. 2001 Oct;21(2-3):153-202. doi: 10.1385/CRIAI:21:2-3:153.
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Pollen allergens and their interrelationships.花粉过敏原及其相互关系。
Clin Rev Allergy. 1985 Jul;3(3):291-318. doi: 10.1007/BF02992997.