Strand C L, Bryant J K, Morgan J W, Foster J G, McDonald H P, Morganstern S L
JAMA. 1982 Oct 1;248(13):1615-8.
Two separate outbreaks of Pseudomonas aeruginosa urinary tract infections (UTIs) were associated with cystoscopy or transurethral prostate resection. The first outbreak was identified after routine bacteremia surveillance demonstrated four cases of P aeruginosa septicemia in a three-month period. A six-month retrospective review of the microbiology records identified 14 cases of P aeruginosa UTI associated with urologic surgery instrumentation. The outbreak terminated after the implementation of two major control measures: (1) replacement of hexachlorophene solution with an iodophor solution for preparing patients and cleaning instruments before disinfection, and (2) weekly gas sterilization of cystoscopy instruments. The second outbreak, consisting of 11 cases of P aeruginosa UTI after transurethral resection of the prostate gland, occurred in a 187-bed community hospital. All available patient isolates were serotype 011, and culture of a rubber adaptor attached to the resectoscope also yielded growth of that serotype. The outbreak promptly terminated when the rubber adaptor was sterilized between cases.
两起独立的铜绿假单胞菌尿路感染（UTIs）暴发与膀胱镜检查或经尿道前列腺切除术有关。第一起暴发是在常规菌血症监测显示三个月内有4例铜绿假单胞菌败血症病例后发现的。对微生物学记录进行的为期六个月的回顾性审查发现了14例与泌尿外科手术器械相关的铜绿假单胞菌尿路感染病例。在实施两项主要控制措施后疫情得到控制：（1）用碘伏溶液替代六氯酚溶液用于患者术前准备和器械消毒前清洁，（2）膀胱镜器械每周进行气体灭菌。第二起暴发发生在一家拥有187张床位的社区医院，包括11例经尿道前列腺切除术后的铜绿假单胞菌尿路感染病例。所有可得的患者分离株均为011血清型，连接到电切镜的橡胶适配器培养物也培养出该血清型。当在病例之间对橡胶适配器进行消毒后，疫情迅速得到控制。
