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单一菌株铜绿假单胞菌引起的医院获得性尿路感染的长期暴发。

Prolonged outbreak of nosocomial urinary tract infection with a single strain of Pseudomonas aeruginosa.

作者信息

Marrie T J, Major H, Gurwith M, Ronald A R, Harding G K, Forrest G, Forsythe W

出版信息

Can Med Assoc J. 1978 Sep 23;119(6):593-6, 598.

PMID:709450
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1818418/
Abstract

Sixty-six hospitalized patients became infected with a single strain of multiply resistant Pseudomonas aeruginosa over a 22-month period. The catheterized urinary tract was the site of the infection in 59 patients (89%). The outbreak was confined to a urology ward until an infected patient from this ward spent 2 weeks in the surgical intensive care unit (SICU). Subsequently patients who acquired the infection in the SICU were discharged to surgical wards throughout the hospital. Urine measuring containers and urometers used in the SICU were the reservoir of the P. aeruginosa; daily sterilization of this equipment terminated the outbreak. Urometers appeared to be the reservoir of the epidemic strain in subsequent outbreaks. Five patients were still infected when they were readmitted 3 to 12 months after the first admission, and therefore represented an additional reservoir of infection.

摘要

在22个月的时间里,66名住院患者感染了单一菌株的多重耐药铜绿假单胞菌。59名患者(89%)的感染部位是导尿管相关的泌尿道。此次暴发局限于泌尿外科病房,直到该病房的一名感染患者在外科重症监护病房(SICU)住了2周。随后,在SICU获得感染的患者被转到医院的各个外科病房。SICU使用的尿液量杯和尿量计是铜绿假单胞菌的储存源;对该设备进行每日消毒后暴发终止。在随后的暴发中,尿量计似乎是流行菌株的储存源。5名患者在首次入院3至12个月后再次入院时仍处于感染状态,因此构成了额外的感染源。

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本文引用的文献

1
The hospital urine bottle and bedpan as reservoirs of infection by Pseudomonas pyocyanea.医院的尿瓶和便盆作为绿脓杆菌感染的储存源。
Lancet. 1958 Feb 22;1(7017):394-7. doi: 10.1016/s0140-6736(58)90715-3.
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Control of Pseudomonas pyocyanea infection in a urological ward.泌尿外科病房绿脓杆菌感染的控制
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Antibiotic susceptibility testing by a standardized single disk method.采用标准化单纸片法进行抗生素敏感性试验。
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Further studies in the pyocine typing of Pseudomonas pyocyanea.绿脓杆菌脓性菌素分型的进一步研究。
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Factors predisposing to bacteriuria during indwelling urethral catheterization.留置导尿期间导致菌尿症的易感因素。
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Nosocomial urinary tract infection with Serratia marcescens: an epidemiologic study.粘质沙雷菌所致医院获得性尿路感染的流行病学研究
J Infect Dis. 1973 Nov;128(5):579-87. doi: 10.1093/infdis/128.5.579.
8
Hospital-acquired infection: present and future impact and need for positive action.医院获得性感染:当前及未来的影响以及采取积极行动的必要性。
Can Med Assoc J. 1974 Apr 6;110(7):769-74.
9
Multidrug-resistant Proteus rettgeri: an emerging problem.多重耐药雷特格变形杆菌:一个新出现的问题。
Ann Intern Med. 1976 Aug;85(2):161-4. doi: 10.7326/0003-4819-85-2-161.
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An outbreak of nosocomial infection due to multiply resistant Serratia marcescens: evidence of interhospital spread.由多重耐药粘质沙雷菌引起的医院感染暴发:医院间传播的证据。
J Infect Dis. 1976 Aug;134(2):181-8. doi: 10.1093/infdis/134.2.181.