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视杆细胞外段内兴奋与适应之间的关系。

The relation between excitation and adaptation within the rod's outer segment.

作者信息

Conner J D

出版信息

Neurosci Lett. 1982 Jun 30;30(3):245-50. doi: 10.1016/0304-3940(82)90407-4.

DOI:10.1016/0304-3940(82)90407-4
PMID:6810239
Abstract

The relation between excitation and adaptation in vertebrate rod photoreceptors was studied by measuring the membrane current of toad rod outer segments in light the darkness. Steady illumination attenuated and sped and rod response to flashes, and it suppressed membrane current noise. When steady illumination ended, the rod's electrical response, the presumably the internal transmitter which caused it, decayed quickly, but adaptation's effects persisted temporarily. This new observation suggests that excitation and adaptation are loosely coupled phenomena which may be mediated by different chemical signals.

摘要

通过测量蟾蜍视杆细胞外段在明、暗中的膜电流,研究了脊椎动物视杆光感受器中兴奋与适应之间的关系。持续光照会减弱并加速视杆细胞对闪光的反应,还会抑制膜电流噪声。当持续光照结束时,视杆细胞的电反应以及可能引发该反应的内部递质会迅速衰减,但适应的影响会暂时持续。这一新观察结果表明,兴奋与适应是可能由不同化学信号介导的松散耦合现象。

相似文献

1
The relation between excitation and adaptation within the rod's outer segment.视杆细胞外段内兴奋与适应之间的关系。
Neurosci Lett. 1982 Jun 30;30(3):245-50. doi: 10.1016/0304-3940(82)90407-4.
2
Two components of electrical dark noise in toad retinal rod outer segments.蟾蜍视网膜视杆细胞外段电暗噪声的两个组成部分。
J Physiol. 1980 Dec;309:591-621. doi: 10.1113/jphysiol.1980.sp013529.
3
Spatial spread of activation and background desensitization in toad rod outer segments.蟾蜍视杆细胞外段激活的空间扩散及背景脱敏
J Physiol. 1981;319:463-96. doi: 10.1113/jphysiol.1981.sp013921.
4
Spread of the light response along the rod outer segment: an estimate from patch-clamp recordings.光反应在视杆细胞外段的传播:来自膜片钳记录的估计
Vision Res. 1986;26(4):535-41. doi: 10.1016/0042-6989(86)90002-7.
5
Calcium and magnesium fluxes across the plasma membrane of the toad rod outer segment.钙和镁跨蟾蜍视杆细胞外段质膜的通量。
J Physiol. 1988 Jan;395:695-729. doi: 10.1113/jphysiol.1988.sp016942.
6
Dependence of the single photon response on longitudinal position of absorption in toad rod outer segments.蟾蜍视杆细胞外段中单光子响应与吸收纵向位置的相关性。
J Physiol. 1983 Oct;343:147-59. doi: 10.1113/jphysiol.1983.sp014886.
7
Electrogenic Na-Ca exchange in retinal rod outer segment.视网膜视杆细胞外段的电致钠钙交换
Nature. 1984;311(5987):661-3. doi: 10.1038/311661a0.
8
The effects of low calcium and background light on the sensitivity of toad rods.低钙和背景光对蟾蜍视杆细胞敏感性的影响。
J Physiol. 1982 Sep;330:307-29. doi: 10.1113/jphysiol.1982.sp014343.
9
Guanosine 3',5'-cyclic monophosphate-activated conductance studied in a truncated rod outer segment of the toad.在蟾蜍截短的视杆外段中研究的3',5'-环磷酸鸟苷激活的电导。
J Physiol. 1988 Jan;395:731-53. doi: 10.1113/jphysiol.1988.sp016943.
10
The membrane current of single rod outer segments.单个视杆细胞外段的膜电流。
J Physiol. 1979 Mar;288:589-611.

引用本文的文献

1
Light-induced changes in GTP and ATP in frog rod photoreceptors. Comparison with recovery of dark current and light sensitivity during dark adaptation.青蛙视杆光感受器中光诱导的GTP和ATP变化。与暗适应过程中暗电流和光敏感度恢复的比较。
J Gen Physiol. 1985 Jan;85(1):107-21. doi: 10.1085/jgp.85.1.107.