[Automated screening and identification of irregular anti-erythrocyte antibodies].

Screening of irregular antibodies performed on a Groupamatic MG50, a two or three channels auto-analyser, and with manual techniques, revealed 4,445 positive sera which were than identified on this auto-analyser system. It was concluded that the "saline-PVP-4 degrees C" channel recovers 17% of the screened sera, which appeared negative with the bromelin and polybrene channels. Saline -4 degrees C detected sera include all of the -M and -P1 specificities and about half of the -K, -Lea and Leb. Identification of cold and namely anti-I antibodies on this channel also leads to an improved analysis of polyspecific sera. The high sensitivity of this 3 channels auto-analyser seems to be optimal for screening and identification of irregular antibodies.