Pryor J P, Pugh R C, Cameron K M, Newton J R, Collins W P
Br J Urol. 1976;48(7):709-17. doi: 10.1111/j.1464-410x.1976.tb06724.x.
The first step in the investigation of infertile men is to obtain 2 seminal analyses 3 days after the previous ejaculation. Clinical assessment of testicular size is an unreliable means of assessing spermatogenesis and is best done by performing bilateral testicular biopsies. Azoospermic men with grossly elevated FSH levels should be advised to consider AID or adoption. Those with normal or mildly elevated FSH levels should undergo testicular exploration in an attempt to correct an obstructive lesion. Azoospermic men with subnormal FSH levels may have an isolated hormone defect which will respond to treatment with Pergonal. Different treatment programmes for oligozoospermic men depending on the results of the FSH and LH assays may lead to a more rational approach to therapy. Infertility associated with varicocele may possibly be associated with a local disturbance of "inhibin" and FSH concentrations.
对不育男性进行检查的第一步是在前次射精3天后进行2次精液分析。通过临床评估睾丸大小来评估精子发生情况并不可靠，最好的方法是进行双侧睾丸活检。对于促卵泡激素（FSH）水平显著升高的无精子症男性，应建议其考虑接受供精人工授精（AID）或领养。FSH水平正常或轻度升高的男性应接受睾丸探查，以试图纠正梗阻性病变。FSH水平低于正常的无精子症男性可能存在单纯的激素缺陷，对此可用 Pergonal 进行治疗。根据FSH和促黄体生成素（LH）检测结果，为少精子症男性制定不同的治疗方案，可能会使治疗方法更加合理。与精索静脉曲张相关的不育可能与局部“抑制素”和FSH浓度紊乱有关。
