Hare J D, Linke C A, Child S Z, Fridd C W, Carstensen E L, Davis H T
J Clin Ultrasound. 1982 Jul-Aug;10(6):257-60. doi: 10.1002/jcu.1870100602.
Hamsters with subcutaneous fibrosarcomas were treated by excision and by exposure to 5-MHz ultrasound for six minutes at an intensity of 3 W/sq cm. Rates for successful elimination of the tumors were between 80% and 90% and were not significantly different for the two methods of treatment. After 30 days, the animals were challenged with the same tumor cells. Animals successfully treated with ultrasound or excision required at least 10 times as many cells to produce a tumor as controls, indicating that eradication of the tumor by ultrasound induced a level of transplant immunity at least as good as that resulting from surgical excision.
对患有皮下纤维肉瘤的仓鼠进行了手术切除治疗，并让其暴露于5兆赫的超声波下，强度为每平方厘米3瓦，持续6分钟。两种治疗方法的肿瘤成功消除率在80%至90%之间，且没有显著差异。30天后，用相同的肿瘤细胞对这些动物进行攻击。经超声波或手术切除成功治疗的动物产生肿瘤所需的细胞数量至少是对照组的10倍，这表明通过超声波根除肿瘤所诱导的移植免疫力水平至少与手术切除所产生的水平一样好。
