Bastin R, Rapin M, Kernbaum S
Pathol Biol (Paris). 1982 Jun;30(6 Pt 2):473-5.
A prospective double-blind study was conducted in patients hospitalized with a staphylococcal infection. The effects of oxacillin (4-6 g/d) and pristinamycin (2-3 g/d) were compared. These were 52 cutaneous infections and 17 other ones. The results of the two antibiotics effects were not different. Tolerance was appreciated in the 82 patients who entered the study: pristinamycin had fewer (but not significantly different) side effects than oxacillin (3/37 vs 9/45). As pristinamycin is active in vitro on at least 95 p. cent of strains, we concluded that it can be the first choice antibiotic in staphylococcal infections when the oral route is possible.
对因葡萄球菌感染住院的患者进行了一项前瞻性双盲研究。比较了苯唑西林（4 - 6克/天）和 pristinamycin（2 - 3克/天）的效果。其中有52例皮肤感染和17例其他感染。两种抗生素的效果没有差异。对进入研究的82例患者的耐受性进行了评估：pristinamycin的副作用比苯唑西林少（但差异不显著）（3/37比9/45）。由于pristinamycin在体外对至少95%的菌株有活性，我们得出结论，当可以采用口服途径时，它可以作为葡萄球菌感染的首选抗生素。
