van den Hout M A, Griez E
Psychother Psychosom. 1982;37(2):75-82. doi: 10.1159/000287556.
Cardiovascular and subjective responses to inhalation of a 35% CO2 mixture were studied in a sample of anxious neurotics. Inhalation of air was used as a placebo control treatment. In comparison with the inhalation of air, CO2 produced a significant drop in diastolic blood pressure. A drop in heart rate frequency was observed both after inhalation of CO2 and air. CO2 inhalation did not produce an average decline in subjective feelings of distress. Explanations of these data are offered and they are compared with earlier findings. Some speculations are made on the clinical usefulness of CO2 inhalation in the treatment of anxious neurotics.
在一组焦虑神经症患者样本中，研究了吸入35%二氧化碳混合气体后的心血管和主观反应。吸入空气作为安慰剂对照治疗。与吸入空气相比，二氧化碳导致舒张压显著下降。吸入二氧化碳和空气后均观察到心率频率下降。吸入二氧化碳并未使主观痛苦感平均降低。文中给出了这些数据的解释，并与早期研究结果进行了比较。对吸入二氧化碳在治疗焦虑神经症中的临床实用性进行了一些推测。
