Godden D J, Willey R F, Fergusson R J, Wright D J, Crompton G K, Grant I W
Thorax. 1982 Jul;37(7):532-4. doi: 10.1136/thx.37.7.532.
In a study of 100 patients undergoing rigid bronchoscopy under intravenous general anaesthesia with oxygen Venturi ventilation no major complications were observed. Minor complications included one adverse reaction to alphaxalone-alphadolone acetate (Althesin), one prolonged episode of laryngeal spasm after removal of the bronchoscope, and subsequent muscle pain attributed to suxamethonium in 36 patients. The last complication occurred significantly less frequently (p less than 0 . 025) in those patients who were pretreated with a small dose of a non-depolarising neuromuscular blocking agent. Serial arterial blood gas sampling in 10 patients showed adequate ventilation during bronchoscopy, but carbon dioxide retention developed in nine cases immediately after the bronchoscope was withdrawn. With adequate precautions, however, the procedure is safe and well tolerated, even in patients with severe impairment of respiratory function.
在一项针对100例接受静脉全身麻醉并采用氧气文丘里通气的硬质支气管镜检查患者的研究中，未观察到重大并发症。轻微并发症包括1例对阿法沙龙-阿法多龙乙酸酯（Althesin）的不良反应、1例在支气管镜移除后持续时间较长的喉痉挛发作，以及36例患者随后出现的因琥珀酰胆碱导致的肌肉疼痛。在预先给予小剂量非去极化神经肌肉阻滞剂治疗的患者中，最后一种并发症的发生频率显著较低（p小于0.025）。对10例患者进行的系列动脉血气采样显示，支气管镜检查期间通气充足，但在支气管镜撤出后，9例患者立即出现了二氧化碳潴留。然而，采取适当的预防措施后，即使是呼吸功能严重受损的患者，该操作也是安全的，且耐受性良好。
