Szekely O, Askanazi J, Rosenbaum S H, Foster R, Milic-Emili J, Kinney J M
Clin Physiol. 1982 Oct;2(5):391-400. doi: 10.1111/j.1475-097x.1982.tb00045.x.
This study was conducted to differentiate the ventilatory and metabolic response to supine exercise at low levels (VO2 less than 1000 ml/min) from the well-documented response to high level upright exercise. Further, the respiratory cycle during exercise is analysed in terms of inspiratory time, flow and expiratory time as well as tidal volume and frequency. Using a canopy system for non-invasive measurement of breathing patterns and gas exchange, nine male subjects were studied while performing steady state (SSE) and progressive exercise (PRE). Work loads were: SSE 1-5 Kgm/sec for 17 min; PRE 1.5, 2.5, 3.75 and 5.0 Kgm/sec with 2 min increments. Total work was the same (1548 Kg . m) in both types of exercise. With SSE tidal volume (Vt) and respiratory rate (integral of) rose 70% and 30%, respectively. Minute ventilation (Ve) rose 113%. With PRE, integral of rose during the first work level, then remained stable, while Vt and Ve rose with each incremental exercise level. In both cases a decrease in expiratory time accounted for the major component of the decrease in total cycle time. With the onset of exercise, the rate of increase of inspiratory time and respiratory frequency exceeded that of tidal volume and inspiratory flow. This would suggest that these two groups of parameters are controlled by separate mechanisms, possibly, timing being under neurogenic control and flow determined by humoral factors. The respiratory quotient decreased with both forms of exercise and remained low throughout the exercise period.
本研究旨在区分低强度（VO2小于1000毫升/分钟）仰卧位运动时的通气和代谢反应与已充分记录的高强度直立位运动时的反应。此外，还从吸气时间、气流、呼气时间以及潮气量和频率方面分析了运动期间的呼吸周期。使用一种用于无创测量呼吸模式和气体交换的罩式系统，对9名男性受试者在进行稳态运动（SSE）和递增运动（PRE）时进行了研究。工作负荷为：SSE为1 - 5千克米/秒，持续17分钟；PRE为1.5、2.5、3.75和5.0千克米/秒，每次增加2分钟。两种运动的总功相同（1548千克·米）。在SSE中，潮气量（Vt）和呼吸频率分别增加了70%和30%。分钟通气量（Ve）增加了113%。在PRE中，呼吸频率在第一个工作水平时增加，然后保持稳定，而Vt和Ve随着每个递增的运动水平而增加。在两种情况下，呼气时间的减少占总周期时间减少的主要部分。运动开始时，吸气时间和呼吸频率的增加速率超过了潮气量和吸气气流的增加速率。这表明这两组参数由不同的机制控制，可能是时间受神经源性控制，而气流由体液因素决定。两种运动形式下呼吸商均下降，且在整个运动期间保持较低水平。
