Finne K, Göransson K, Winckler L
Int J Oral Surg. 1982 Aug;11(4):236-9. doi: 10.1016/s0300-9785(82)80073-2.
29 patients with oral lichen planus and amalgam fillings were patch tested for contact allergy to dental materials. 18 of these patients (62%) had a contact allergy to mercury. In a control material, the frequency of mercury allergy was 3.2%. In 3 of the patients the lesions healed completely after removal of the amalgam fillings. On the basis of these findings it is recommended that all amalgam fillings be removed after a positive patch test to mercury, as a step in the treatment of oral lichen planus.
对29例患有口腔扁平苔藓且有汞合金填充物的患者进行了牙科材料接触性过敏斑贴试验。其中18例患者(62%)对汞存在接触性过敏。在对照人群中,汞过敏的发生率为3.2%。3例患者在去除汞合金填充物后病损完全愈合。基于这些研究结果,建议在斑贴试验对汞呈阳性反应后,作为口腔扁平苔藓治疗的一个步骤,应去除所有汞合金填充物。