Grange J, Collins C, Yates M
J Epidemiol Community Health. 1982 Sep;36(3):157-61. doi: 10.1136/jech.36.3.157.
During the eight years 1973-80 the Public Health Laboratory Service Regional Centre for Tuberculosis Bacteriology received cultures of mycobacteria from 2339 patients with tuberculous lymphadenitis. Of these, 2272 were M tuberculosis (2207 human and 65 bovine strains) and 67 were other mycobacterial species, usually M avium and its intracellulare variant. Disease due to the human strains of M tuberculosis occurred most often in young women of Asian ethnic origin. Many bovine strains isolated from Asian patients differ from the classical bovine type in being sensitive to pyrazinamide: the origin of these strains, whether from other people or from cattle, is unknown. Lymphadenitis due to bovine strains tended to occur in an older age group than the human strains and probably include relatively more cases of reactivation diseases. Infection caused by the other mycobacterial species occurred mainly in young children of European origin. Tuberculosis, therefore, remains an important cause of lymphadenopathy in Britain.
在1973年至1980年的八年期间,公共卫生实验室服务结核病细菌学区域中心收到了2339例结核性淋巴结炎患者的分枝杆菌培养物。其中,2272例为结核分枝杆菌(2207例人型菌株和65例牛型菌株),67例为其他分枝杆菌种,通常是鸟分枝杆菌及其胞内变种。由人型结核分枝杆菌菌株引起的疾病最常发生在亚洲裔年轻女性中。从亚洲患者中分离出的许多牛型菌株与经典牛型菌株不同,对吡嗪酰胺敏感:这些菌株的来源,无论是来自其他人还是牛,都不清楚。由牛型菌株引起的淋巴结炎往往比人型菌株发生在年龄较大的人群中,并且可能包括相对较多的再激活疾病病例。由其他分枝杆菌种引起的感染主要发生在欧洲裔幼儿中。因此,在英国,结核病仍然是淋巴结病的一个重要原因。