Golbus M S, Stephens J D, Cann H M, Mann J, Hensleigh P A
Prenat Diagn. 1982 Jul;2(3):149-56. doi: 10.1002/pd.1970020302.
A series of 8009 genetic amniocenteses were retrospectively examined to evaluate the relationship of the procedure to Rh isoimmunization. Of the 615 Rh negative women giving birth to Rh positive infants and estimated to be at risk, thirteen (2.1 per cent) were sensitized subsequently to the amniocentesis. Eleven of the sensitizations occurred early in the programs, and a combination of experience and ultrasound performed concurrently with the amniocentesis appear to have reduced the risk of isoimmunization to that of control data from the literature.
回顾性检查了8009例基因羊膜穿刺术，以评估该操作与Rh血型免疫的关系。在615名Rh阴性且生育Rh阳性婴儿并被估计有风险的妇女中，有13名（2.1%）随后因羊膜穿刺术而致敏。其中11例致敏发生在该项目早期，同时进行的经验积累和超声检查似乎已将免疫风险降低至文献中对照数据的水平。
