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哥本哈根尸体肾供体和受体的人类白细胞抗原-DR分型

HLA-DR typing in cadaver kidney donors and recipients in Copenhagen.

作者信息

Thomsen M, Astrup L, Jakobsen B, Morling N, Platz P, Ryder L P, Svejgaard A, Løkkegaard H, Ladefoged J, Thaysen J H

出版信息

Scand J Urol Nephrol Suppl. 1981;64:79-86.

PMID:6815796
Abstract

Among 224 cadaver kidney transplantations performed since Spring 1977, successful DR typing of both donor and recipient could be done in 149 cases. Assessment of DR match grade and clinical data was done independently. The minimum observation time was 3 months and the time of follow up was 1 December, 1980. There was an effect of DR matching which became significant when only 1. transplants were considered and high risk recipients (i.e. diabetics) excluded. Transfusions were of minor importance on graft survival and the difference was only obvious in the first year after transplantation. Matching for HLA-A, B antigen had no obvious effect on graft survival in this material.

摘要

在1977年春季以来实施的224例尸体肾移植中,149例供体和受体的DR分型均可成功完成。DR匹配等级评估和临床数据评估是独立进行的。最短观察时间为3个月,随访时间至1980年12月1日。存在DR匹配效应,当仅考虑1.移植且排除高危受者(即糖尿病患者)时,该效应变得显著。输血对移植物存活影响较小,差异仅在移植后第一年明显。在该研究材料中,HLA - A、B抗原匹配对移植物存活无明显影响。

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