McClure H M, Chandler F W
Vet Pathol Suppl. 1982 Sep;7:193-209.
Approximately 3,000 microslides of hematoxylin and eosin (HE)-stained sections of pancreas from 1,000 nonhuman primates were reviewed. Sections were from 557 females and 443 males; 658 were adults of unknown age and 342 were laboratory-born animals of known age. The latter included 94 animals less than one year old, 92 from one to five years old, and 156 from five to more than 20 years old. There were 326 squirrel monkeys, 319 rhesus monkeys, 100 great apes, 123 other macaques, 61 other Old World monkeys, 39 other New World monkeys, and 32 prosimians. Pancreatic lesions of varied severity found in 187 (18.7%) of these nonhuman primates included focal parenchymal or periductal accumulations of mononuclear inflammatory cells with varied degrees of periductal fibrosis in 77; hyalinized islets (amyloidosis) in 29; acute or chronic diffuse pancreatitis in 18; chronic focal pancreatitis with or without ductal hyperplasia in ten; neoplasms in 11; hemorrhage of the parenchyma or islets in eight; parasites in seven; lymphoid or ectopic splenic nodules of the parenchyma in six; acinar ectasia in six; focal parenchymal fat in six; ectopic pancreas in four; parenchymal cysts without fibrosis in three; acinar cell atrophy in one; and cystic fibrosis-like changes in one.
对来自1000只非人灵长类动物的约3000张苏木精和伊红（HE）染色的胰腺切片进行了检查。切片来自557只雌性和443只雄性动物；658只为年龄不详的成年动物，342只为已知年龄的实验室出生动物。后者包括94只小于1岁的动物、92只1至5岁的动物和156只5至20岁以上的动物。其中有326只松鼠猴、319只恒河猴、100只大猩猩、123只其他猕猴、61只其他旧世界猴、39只其他新世界猴和32只原猴。在这些非人灵长类动物中有187只（18.7%）发现了不同严重程度的胰腺病变，其中77只出现局灶性实质或导管周围单核炎性细胞聚集并伴有不同程度的导管周围纤维化；29只出现胰岛玻璃样变（淀粉样变性）；18只出现急性或慢性弥漫性胰腺炎；10只出现慢性局灶性胰腺炎伴或不伴导管增生；11只出现肿瘤；8只出现实质或胰岛出血；7只出现寄生虫；6只出现实质内的淋巴样或异位脾结节；6只出现腺泡扩张；6只出现局灶性实质脂肪；4只出现异位胰腺；3只出现无纤维化的实质囊肿；1只出现腺泡细胞萎缩；1只出现囊性纤维化样改变。
