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小肠旁路手术后青霉素和对乙酰氨基酚的吸收情况。

Absorption of penicillin and paracetamol after small intestinal bypass surgery.

作者信息

Terry S I, Gould J C, McManus J P, Prescott L F

出版信息

Eur J Clin Pharmacol. 1982;23(3):245-8. doi: 10.1007/BF00547562.

DOI:10.1007/BF00547562
PMID:6816618
Abstract

Drug absorption was studied in morbidly obese patients before and after jejunoileal bypass. The absorption of phenoxymethyl penicillin was considerably increased whilst that of paracetamol was unchanged.

摘要

在空肠回肠分流术前后对病态肥胖患者的药物吸收情况进行了研究。苯氧甲基青霉素的吸收显著增加，而对乙酰氨基酚的吸收则没有变化。

相似文献

1
Absorption of penicillin and paracetamol after small intestinal bypass surgery.小肠旁路手术后青霉素和对乙酰氨基酚的吸收情况。
Eur J Clin Pharmacol. 1982;23(3):245-8. doi: 10.1007/BF00547562.
2
A comparison of the absorption of effervescent preparations of paracetamol and penicillin V (phenoxymethylpenicillin) with solid dose forms of these drugs.
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Effects of jejunoileal bypass on the enterohepatic circulation of bile acids, bacterial flora in the upper small intestine, and absorption of vitamin B12.空肠回肠旁路术对胆汁酸肝肠循环、小肠上段细菌菌群及维生素B12吸收的影响。
Metabolism. 1983 Dec;32(12):1133-41. doi: 10.1016/0026-0495(83)90060-4.
4
Vitamin B12 absorption following human intestinal bypass surgery.
Am J Dig Dis. 1977 Dec;22(12):1069-71. doi: 10.1007/BF01072859.
5
Sex hormone levels and intestinal absorption of estradiol and D-norgestrel in women following bypass surgery for morbid obesity.
Int J Obes. 1982;6(1):91-6.
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Fat digestion after jejunoileal bypass operation for obesity.肥胖症空肠回肠旁路手术后的脂肪消化
Scand J Gastroenterol. 1976;11(5):491-5.
7
Phenytoin absorption following jejunoileal bypass.空肠回肠旁路术后苯妥英钠的吸收情况
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Jejunoileal bypass for the treatment of morbid obesity.空肠回肠旁路术治疗病态肥胖症。
Int Surg. 1980 Mar-Apr;65(2):103-5.
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The absorption of oxalate, calcium, and fat after jejunoileal bypass. A prospective study.空肠回肠旁路术后草酸盐、钙和脂肪的吸收。一项前瞻性研究。
Scand J Gastroenterol. 1980;15(3):343-8. doi: 10.3109/00365528009181481.
10
Changes in body composition after jejunoileal bypass in morbidity obese patients.病态肥胖患者空肠回肠旁路术后身体成分的变化。
Am J Surg. 1972 Jan;123(1):49-56. doi: 10.1016/0002-9610(72)90310-8.

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Drug absorption in bariatric surgery patients: A narrative review.肥胖症手术患者的药物吸收：一篇叙述性综述。
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Oral drug dosing following bariatric surgery: General concepts and specific dosing advice.减重手术后的口服药物给药：一般概念和具体给药建议。
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Systematic review of drug bioavailability following gastrointestinal surgery.胃肠道手术后药物生物利用度的系统评价。

本文引用的文献

1
RELATION OF MASSIVE BOWEL RESECTION TO GASTRIC SECRETION.大肠大部切除术与胃液分泌的关系
N Engl J Med. 1965 Mar 11;272:509-14. doi: 10.1056/NEJM196503112721004.
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Current status of jejunoileal bypass for obesity.空回肠分流术治疗肥胖症的现状
Lancet. 1981 Jan 10;1(8211):93. doi: 10.1016/s0140-6736(81)90022-2.
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Surgical treatment of obesity.肥胖症的外科治疗
Eur J Clin Pharmacol. 2018 Dec;74(12):1531-1545. doi: 10.1007/s00228-018-2539-9. Epub 2018 Aug 22.
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Oral Contraceptives after Bariatric Surgery.减肥手术后的口服避孕药
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Lithium toxicity after Roux-en-Y bariatric surgery.Roux-en-Y胃旁路手术后的锂中毒
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6
Vitamin, mineral, and drug absorption following bariatric surgery.减重手术后的维生素、矿物质和药物吸收。
Curr Drug Metab. 2012 Nov;13(9):1345-55. doi: 10.2174/138920012803341339.
7
Trends in oral drug bioavailability following bariatric surgery: examining the variable extent of impact on exposure of different drug classes.减重手术后口服药物生物利用度的变化趋势：不同药物类别的暴露影响程度不一。
Br J Clin Pharmacol. 2012 Nov;74(5):774-87. doi: 10.1111/j.1365-2125.2012.04284.x.
8
Drug absorption in gastrointestinal disease and surgery. Clinical pharmacokinetic and therapeutic implications.胃肠道疾病与手术中的药物吸收。临床药代动力学及治疗意义。
Clin Pharmacokinet. 1991 Dec;21(6):431-47. doi: 10.2165/00003088-199121060-00004.
Am J Surg. 1969 Aug;118(2):141-7. doi: 10.1016/0002-9610(69)90113-5.
4
Effect of small-bowel bypass on gastric secretion in obese patients.小肠旁路手术对肥胖患者胃分泌的影响。
Can J Surg. 1968 Jul;11(3):365-8.
5
Absorption of digoxin in patients with malabsorption syndromes.吸收不良综合征患者对地高辛的吸收情况。
N Engl J Med. 1971 Jul 29;285(5):257-9. doi: 10.1056/NEJM197107292850504.
6
Absorption of phenoxymethyl penicillin in patients with steatorrhoea.脂肪泻患者对苯氧甲基青霉素的吸收情况。
Australas Ann Med. 1968 Feb;17(1):63-5. doi: 10.1111/imj.1968.17.1.63.
7
Tritiated digoxin. XXII. Absorption and excretion in malabsorption syndromes.氚标记地高辛。XXII。吸收不良综合征中的吸收与排泄。
Am J Med. 1974 Apr;56(4):437-42. doi: 10.1016/0002-9343(74)90473-2.
8
Pharmacological modification of gastric emptying: effects of propantheline and metoclopromide on paracetamol absorption.胃排空的药理学调节：丙胺太林和甲氧氯普胺对扑热息痛吸收的影响。
Br Med J. 1973 Mar 10;1(5853):587-9. doi: 10.1136/bmj.1.5853.587.
9
Intestinal adaptation.
N Engl J Med. 1973 Mar 8;288(10):520-1. doi: 10.1056/NEJM197303082881011.
10
Gas-liquid chromatographic estimation of paracetamol.对乙酰氨基酚的气-液色谱法测定
J Pharm Pharmacol. 1971 Oct;23(10):807-8. doi: 10.1111/j.2042-7158.1971.tb08613.x.