Seager R D, Ayala F J
Genetics. 1982 Nov;102(3):467-83. doi: 10.1093/genetics/102.3.467.
The nature of fitness interactions is an important, yet unsolved, question in population genetics. We compare the egg-to-adult viability of individuals homozygous for either a second or a third chromosome with the viability of individuals homozygous for both chromosomes simultaneously. On the average, the viability of the two-chromosome homozygotes is somewhat greater than expected assuming that the fitnesses of the single-chromosome homozygotes interact in a multiplicative fashion. This result differs from previous observations that indicate either no significant deviations from the expectation or lower-than-expected average fitnesses for the double homozygotes.
适合度相互作用的本质是群体遗传学中一个重要但尚未解决的问题。我们比较了仅一条第二染色体或第三染色体纯合的个体从卵到成虫的存活率与两条染色体同时纯合的个体的存活率。平均而言,假设单染色体纯合子的适合度以乘法方式相互作用,那么两条染色体纯合子的存活率略高于预期。这一结果与之前的观察结果不同,之前的观察结果表明,双纯合子要么没有显著偏离预期,要么平均适合度低于预期。